Hi Greg,
Just to be sure, I was talking about a midi device with it's own USB connection. For example, and among others, my "studiologic vmk-88 plus" (By Fatar). Only functions by connecting it with Midi to my Tascam US-122, and the Tascom directly with USB to USB of a laptop. If I don't use the Tascam and connect the keyboard directly to any USB port (1.0 or 2.0) (I have tested this with 2 Toshiba's an Acer and a Fujitsu) Fujitsu and Desktop, no problem. For the other laptops I needed a USB-hub (not an MIDI to USB converter). It's even more strange when the system tells you that the USB device Studiologic has been connected, but it won't function unless I make use of a USB-hub. And the Studiologic is not the only device that showed this problem. Even (and now it comes) the ION keyboard that comes along with Pianissimo only works with help of a USB-HUB. And like erlier mentioned, without the HUB Windows tells me that the device is connected but Pianissimo doesn't respond and even tells me there is no device, like the other VSTi's or stand alones.

cheers, I wanted to shares this information, to prevent that people unnecessarilly damage the registry before trying this option. And I love the sound of Pianissimo.